Title

Exogenous Lipoid Pneumonia Diagnosed on Paediatric Autopsy Examination – A Case Series.

Authors

Pawan Sabale, Sharad Gaikwad, Charvi Sankholkar, Jayati Gupta.

Abstract

Background: Lipoid pneumonia is caused due to deposition of foreign body of lipid nature within the lung parenchyma which may enter directly through upper respiratory tract or it may be secreted distal to the obstruction in terminal bronchioles. In this case series, we aim to shed light over this rare and underdiagnosed cause of pneumonia which is often missed on clinical examination as well as on autopsy. Methods: The information provided through Inquest report was analyzed. During autopsy tissues for histopathology were preserved. Histopathological examination of lung parenchyma was carried out to examine the features consistent with lipoid pneumonia. Results: Cytological demonstration of lipid-laden macrophages and histopathological examination showing bacterial colonies and lipid molecules in lung parenchyma is consistent with diagnosis of exogenous Lipoid pneumonia in the studied cases. Conclusion: A vast majority of Lipoid Pneumonia cases remain undiagnosed as Histopathological analysis is not done. We would like to comment that there are certain events which leads to the deposition of lipids in lung parenchyma thereby leading to the development of ‘lipoid pneumonia’ highlighting the importance of histopathological examination in cases with such histories.

Key words

Lipid Pneumonia, Aspiration Pneumonia, Lipid Laden Macrophages, Paediatric Autopsy.

DOI

 10.59988/jfmsl.vol.33issue1.10